Prof. Pietro MORTINI

Though rare, cauda equina syndrome is a severe neurological disorder that can lead to incontinence and even permanent paraplegia if left untreated.

The individual nerve roots at the end of the spinal cord, which provide motor and sensory function to the legs and the bladder, continue along in the spinal canal. The cauda equina (Latin for “horse’s tail”) refers to the sac of nerve roots with a common covering before the end of the spinal cord in the lumbar region.

Cauda equina syndrome most commonly results from a massive disc herniation in the lumbar region. A disc herniation occurs when one of the soft flexible discs that functions as an elastic shock absorber between the bones of the spinal column displaces from its normal position.

The herniation occurs after the disc begins to break down with aging and can be precipitated by stress or a mechanical problem in the spine. The result is that the softer, center portion of the disc pushes out and causes pressure on the nerve roots in the lumbar spine. Cauda equina syndrome is caused by this compression of the nerve roots.

Symptoms

Cauda equina syndrome is accompanied by a range of symptoms, the severity of which depend on the degree of compression and the precise nerve roots that are being compressed. Symptoms may include

Diagnosis

Cauda equina syndrome is difficult to diagnose. It is rare and its symptoms mimic those of other conditions. Besides a herniated disk, other conditions with similar symptoms to cauda equina syndrome include

Another difficulty in diagnosing cauda equina syndrome is that its symptoms may vary in intensity and evolve slowly over time.

Synthoms that indicate cauda equina syndromein someone with back pain include

The presence of these symptoms warn of cauda equina compression.

Red flags also may be present in a patient’s history. Recent trauma, a history of cancer or a severe infection may predispose a person to cauda equina syndrome. Any of these diseases can involve the discs or the bones of the lumbar spine and result in cauda equina syndrome. Other conditions that may rarely lead to cauda equina syndrome include osteoporotic vertebral fractures and spinal stenosis.

Physicians suspecting the syndrome look also for reflex abnormalities such as

MRI (magnetic resonance imaging) or myelograms are diagnostic tools valuable in discovering cauda equina syndrome. A myelogram is a liquid dye injected into the spinal column. A myelogram can show pressure on the cauda equina from herniated discs and other conditions.

Cauda equina syndrome occurs primarily in adults, though trauma-related cauda equina syndrome is not age specific.

Treatment

Treatment of cauda equina syndrome is necessary to maximize the likelihood of the bladder and bowel function. Treatment may also prevent further weakness in the lower extremities. Left untreated, cauda equina syndrome can result in paraplegia.

Prompt surgery is the best treatment for patients with cauda equina syndrome. Treating patients within 48 hours after the onset of the syndrome provides a significant advantage in improving sensory and motor deficits as well as urinary and rectal function.

Even patients who undergo surgery after the 48-hour ideal time frame may experience significant improvement. Although short-term recovery of bladder function may lag behind reversal of lower extremity motor deficits, the function may continue to improve years after surgery. Following surgery, drug therapy coupled with intermittent self-catheterization can help lead to slow but steady recovery of bladder and sphincter function.

Although steroids have proven useful in the treatment of spinal cord injury and some physicians advocate steroids for cauda equina syndrome, no evidence suggests that they are useful in treatment of cauda equina compression. In fact, some physicians point to the potential risks of high-dose steroid use and do not advocate their use to treat cauda equina syndrome.

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